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NCT06877572Recruiting

Weight Loss Management in Endometrial Cancer Survivors

University of Kansas Medical Center

Start Date

3/25/2025

Completion Date

10/1/2030

Summary

This study is being done to understand how oncologists can engage a multidisciplinary team to help endometrial cancer survivors with obesity to engage in a weight management program and potentially start a weight loss medication. Obesity often impacts the future health and longevity of early-stage endometrial cancer survivors more than their cancer diagnosis. Patients will be referred to the KUMC OB/Gyn weight management clinic to discuss weight management options. * If patients decide to use medications for weight loss, then the study will collect data from their chart that is recorded as part of routine monitoring for patients on weight loss medications. * If patients decide not to use any medications, the study will monitor physical exam and lab data collected as part of their routine medical care. The study will also try to understand reasons why patients did or did not start using a weight loss medication.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * ≥18 years old * ECOG 0-2 * BMI ≥ 30kg/m2 * Completed surgical staging with no evidence of residual disease * Endometrioid endometrial adenocarcinoma, p53 wild type * Stage 1 * Undergoing active surveillance +/- brachytherapy Exclusion Criteria: * Unable to participate in behavior weight loss * Stroke, heart attack, end stage liver disease, or end stage kidney disease during the last 6 months. * Currently on a GLP-1 agonist * Currently on insulin

Interventions

BEHAVIORAL

Weight loss with pharmacotherapy

BEHAVIORAL

Weight loss without pharmacotherapy

Interested in This Trial?

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Conditions

Endometrial Cancer SurvivorsWeight ManagementEarly Stage Endometrial Cancer

Locations

University of Kansas Medical Center

Kansas City, Kansas 66160

United States