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NCT06903975PHASE4RecruitingAccepts Healthy Volunteers

BoTox Into the Sternocleidomastoid Muscles (SCM)

Boston Medical Center

Start Date

5/14/2025

Completion Date

8/1/2026

Summary

Botulinum toxin injections have been used both in the face and neck for many years. However, injection into the sternocleidomastoid muscle (SCM) has only been done to treat neck spasms. In this study botulinum toxin will be injected into the SCM to determine if this will result in a temporary slimming effect on the neck and produce a more feminine, youthful neck contour.

Detailed Description

The specific study objectives are to determine if: * the neck circumference is decreased at 4 weeks after botulinum toxin (prabotulinumtoxinA-xvfs) injection. * patients can appreciate a difference in their neck contour, self-confidence, and the way they perceive themselves post-injection via an aesthetics outcome and a neck perception survey. * injection of the botulinum toxin into the sternocleidomastoid muscle is safe to perform based on adverse events.

Eligibility Criteria

Age Range: 18 years to 65 years

Inclusion Criteria: * Age eligible individual seeking a more feminine neck appearance Exclusion Criteria: * Prior neuromodulator injections in the sternocleidomastoid muscles (SCM) within the past year * Current anticoagulant use * Body mass index (BMI) \>30 * Anticipation of significant weight gain or loss during the study period (e.g. patients taking or planning to take within the study period a semaglutide medication.) * Prior allergy to botulinum toxin A * Currently pregnant or breastfeeding

Interventions

DRUG

prabotulinumtoxinA-xvfs

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Conditions

Neck Muscle Issue

Locations

The Spiegel Center

Newton, Massachusetts 02459

United States