NCT06930976NARecruitingAccepts Healthy Volunteers

Tracing Of Real-time glu13Cose Metabolism in Human Immune Cells

Vanderbilt University Medical Center

Start Date

10/1/2025

Completion Date

6/30/2027

Summary

The purpose of this study is to understand how cells of the immune system use the common sugar glucose to fuel energy production and as a building block within the cell. Investigators will intravenously infuse a non-radioactive glucose tracer into participants over a few hours and collect immune cells from the blood to track uptake and usage of this glucose within these immune cells.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Adults aged 18 or older Exclusion Criteria: * Pregnant * Prisoner or in police custody * Uncontrolled hyperglycemia/diabetes * Current participation in another study where the total volume of blood drawn, when added to this study blood draw volume, exceeds 500cc in an 8 week period * Any medical issue or pharmacologic exposure which, in the opinion of the study investigator, that might interfere with the study objectives * Any reason which, in the opinion of the study investigator, adds additional risk to the participant

Interventions

DRUG

13C6-Glucose

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Conditions

GlucoseMetabolismIsotope LabelingImmune System and Related Disorders

Locations

Vanderbilt University Medical Center

Nashville, Tennessee 37212

United States