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NCT06932783NARecruiting

Remote Electrical Stimulation for Pain and Depression Treatment in Cirrhosis

University of Michigan

Start Date

7/22/2025

Completion Date

7/1/2027

Summary

This study is being done to better understand how the study team can treat pain for people with cirrhosis and depression. Enrolled participants on this feasibility study will be randomized to Transcutaneous Electrical Acustimulation (TEA) or sham TEA.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Diagnosis of cirrhosis - must meet the criteria as outlined in the protocol * Chronic pain (Patient self-reports ≥ 4 on the 0-10 scale for \>50% of days within 3- months) * Depression (in at least half of participants) - must meet the criteria as outlined in the protocol * English speaking * Willing to use a Transcutaneous Electrical Acustimulation device Exclusion Criteria: * Dementia and/or severe cognitive impairment * Unable or unwilling to provide consent * Expected to undergo liver transplant in next 24 weeks * No email address * Deemed unsuitable by the study investigator

Interventions

DEVICE

Transcutaneous Electrical Acustimulation (TEA)

DEVICE

Sham Transcutaneous Electrical Acustimulation (TEA)

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Conditions

Cirrhosis

Locations

University of Michigan

Ann Arbor, Michigan 48109

United States