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NCT06948162RecruitingAccepts Healthy Volunteers

Exploration of the Utility of Dental-dedicated MRI for Dentistry

University of Minnesota

Start Date

3/14/2025

Completion Date

12/31/2027

Summary

This description observational research is comparative in design, that is comparing existing standard clinical dental images, not obtained in this study, to test (i.e., ddMRI) images. The standard clinical dental images consist of radiographs, such as bitewings, periapical, panoramic, cone-beam CT, and medical CT, as well medical MRIs of the temporomandibular joints (TMJ).The conceptualization of research questions, study designing, and interpretation of imaging data has and will involve content expertise in all ddMRI research.

Detailed Description

Patients recruited from dental clinics at the University of Minnesota School of Dentistry will be screened for eligibility and asked to complete an MRI safety screening questionnaire. Eligible individuals will be invited to participate in at least one study visit, during which an MRI scan will be performed. At the end of the session, participants will complete a short questionnaire about their experience during the scan.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: 1. Patient Age: 18 years old or older 2. Receiving imaging for routine dental care 3. Does not have a serious medical condition 4. Is not pregnant or is not potentially pregnant 5. Is willing and able to give consent in English 6. Has the ability to manage their own calendar and schedule appointments 7. Willing to have a separate 2-hour appointment to have an MRI Exclusion Criteria: 1. Unable to consent to participant in English 2. Serious health condition, which includes but not limited to renal failure/on dialysis, unstable heart disease (uncontrolled arrhythmia, cardiomyopathy and/or unable to lay flat, within 1 month of cardiac catheterization or myocardial infarction), unstable cerebral vascular disease (within 1 month of stroke and/or stent placement), diabetes (type I or II) not controlled by medication or diet, uncontrolled seizures, uncontrolled hyperthyroidism, non-allergic bronchospasm (chronic obstructive pulmonary disease and emphysema), uncontrolled movement disorder, and liver failure 3. Pregnant and/or intending to become pregnant, 4. Prisoner and/or not able to manage their own scheduling 5. Screen positive on MR safety questionnaire, specifically including people that have worked with or otherwise been exposure to metal particles and have the potential for such particles to be embed within them.

Interventions

DEVICE

dental-dedicated MRI (ddMRI)

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Conditions

Dental CrowdingDental Occlusion, TraumaticDental PainTMD/Orofacial PainTMDOrthodonticsEndodontic DiseaseOrthodontic Treatment

Locations

Orofacial MRI Center at UMN

Minneapolis, Minnesota 55455

United States