Post-Stroke Aphasia TMS
Start Date
9/1/2025
Completion Date
12/31/2036
Summary
The investigator proposes to examine the effects of excitatory transcranial magnetic stimulation (TMS) combined with semantic feature analysis (SFA) language therapy to improve word-finding abilities in stroke survivors with aphasia (SWA).
Detailed Description
In this project, the investigator will use functional neuroimaging and inhibitory TMS to determine precise therapy-responsive targets for excitatory TMS therapy with SFA. One group of stroke survivors will receive SFA + TMS targeting the precision site, and another group will receive SFA + TMS targeting a control site. The primary outcome will be changes in picture naming accuracy. We expect that excitatory TMS targeting a precision site would result in larger improvements in naming accuracy than TMS targeting a control site. Results will provide the efficacy of precision TMS in post-stroke aphasia.
Eligibility Criteria
Age Range: 18 years to No maximum
Interventions
Precision TMS with SFA
Control TMS with SFA
Conditions
Locations
Medical College of Wisconsin
Milwaukee, Wisconsin 53226
United States