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NCT06975046NARecruitingAccepts Healthy Volunteers

Aerodynamic Measurements in the Pediatric Population

University of Wisconsin, Madison

Start Date

12/22/2025

Completion Date

12/1/2030

Summary

The goal of this clinical trial is to create a vocal health database of people aged 4-65 with no diagnosed voice pathology. The main question it aims to answer is: * what is the best way to assess pediatric voices; and, * what are the differences between healthy and dysphonic pediatric voices? Participants will complete one 60 minute session involving one of three types of aerodynamic interruption.

Detailed Description

The primary goals of this research are to develop noninvasive aerodynamic assessments specific to the pediatric population, and to describe differences between healthy and dysphonic pediatric voices between the ages of 4-17 years. An adult cohort (ages 18-65) will function as a comparison group for incomplete interruption. To account for challenges associated with pediatric data collection, we will modify our current devices and methods of aerodynamic assessment to be better suited for use with the pediatric population and aim to increase measurement reliability in younger subjects. Our proposed modifications include shorter trial times, auditory masking, the use of cheek restraints, and gamification. After identification of optimal data collection conditions for each method, we will compare these in a large group of children with normal voice. These data will be compared to data from children with vocal fold nodules or polyp. All data will be compiled into a pediatric vocal health database.

Eligibility Criteria

Age Range: 4 years to 65 years

Inclusion Criteria - Healthy Control: * Age 4-65 years * Normal voice * No history of voice or other pertinent health disorders Exclusion Criteria - Healthy Control: * Neuromuscular disorder affecting the larynx * History of respiratory or laryngeal disease * History of smoking * Hearing impairment * Cognitive impairment that might impact ability to perform the tasks required by the study Inclusion Criteria - Abnormal Voice: * Age 4-17 * Laryngeal pathology Exclusion Criteria - Abnormal Voice: * No laryngeal disorder

Interventions

DEVICE

Complete airflow interruption

DEVICE

Incomplete airflow interruption

DEVICE

Airflow redirection

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Conditions

Normal Voice

Locations

University of Iowa

Iowa City, Iowa 52242

United States

University of Wisconsin - Madison

Madison, Wisconsin 53705

United States