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NCT06976736Recruiting

A Long Term Follow-up Study of TScan TCR-T Products

TScan Therapeutics, Inc.

Start Date

9/9/2025

Completion Date

9/1/2040

Summary

The purpose of this Long-Term Follow-Up (LTFU) study is to monitor participants who have previously received TSC-100 or TSC-101 TCR-T therapies in the TSCAN-001 study. Participants will be monitored for 15 years from the date of TCR-T cell therapy administration to assess long-term safety and efficacy.

Detailed Description

Participants will enroll in this LTFU study after completing the TSCAN-001 interventional trial. No additional study drug will be administered; however, participants may receive other cancer treatments as needed while being monitored for long-term safety. Enrollment will occur after completion of the TSCAN-001 study, and participants will be monitored for safety and efficacy over a 15 year period.

Eligibility Criteria

Age Range: 18 years to 110 years

Inclusion Criteria: * Participants who received a TCR-T cellular therapy in a clinical study sponsored by TScan Therapeutics. * Signed informed consent. Exclusion Criteria: * None

Interventions

OTHER

Observational

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Conditions

AMLALLMDS

Locations

City of Hope

Duarte, California 91010

United States

Mount Sinai

New York, New York 10029-6696

United States