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NCT06998966NARecruiting

Optimizing Proton Pump Inhibitors (PPI) Prescribing With EHR-Based Decision Support

University of California, Los Angeles

Start Date

6/1/2026

Completion Date

6/1/2027

Summary

The proposed study is a quality improvement initiative designed to rigorously evaluate new variations of UCLA Health's proton pump inhibitor (PPI) order panels, building on internal quality improvement efforts to optimize prescribing workflows within the Electronic Health Record (EHR). PPIs are notoriously overprescribed, and the study team has identified that the CareConnect default prescription setting of 90 days with three refills (360 pill days) exceed standard guidelines (in most cases, 60 pill days). It is unclear whether this is the most appropriate workflow. Given that deprescribing PPIs carries minimal risk for most patients, this initiative will assess whether modifying defaulted prescription lengths influences prescribing behavior while ensuring physicians retain full decision-making authority. This evaluation of PPI order panel variations is embedded within UCLA's existing EHR system, ensuring that changes are tested pragmatically within routine workflows. The study aims to determine whether small adjustments to the order panel can better align prescribing patterns with clinical best practices while maintaining physician autonomy.

Eligibility Criteria

Age Range: 50 years to No maximum

Inclusion Criteria: * UCLA Health primary care physicians who have a clinical full-time equivalency of at least 25%. Exclusion Criteria: * Physicians with a clinical full-time equivalency of less than 25%

Interventions

BEHAVIORAL

Algorithmic Defaulting (Indication-Based Default)

BEHAVIORAL

Active Physician Choice

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Conditions

Prescribing Patterns, PhysicianPhysician's Practice PatternsDrug Utilization Review

Locations

UCLA Health System

Los Angeles, California 90024

United States