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NCT07003113NARecruiting

Ischemic Preconditioning in Osteoarthritis and Back Pain

University of Illinois at Chicago

Start Date

9/12/2025

Completion Date

12/31/2026

Summary

We are examining the use of restricted blood flow, through full occlusion, on a single thigh for 50 minutes (5 minutes on, 5 minutes off), completed every other day for 2 weeks to improve function in individuals with knee osteoarthritis and low back pain.

Eligibility Criteria

Age Range: 50 years to No maximum

Inclusion Criteria: * Reported Knee Pain using ACR Criteria * Reported Back Pain using ODI Criteria \> 12 * Ability to walk for at least 3 minutes without the use of aids * Ability to provide written informed consent Exclusion Criteria: * Younger than 50 years old * History of Knee or Hip Replacements * History of steroid injection within the previous 6 months * Presence of neuromuscular joint condition that affects lower extremity function * History of blood clots in the leg or any condition in which compression of the thigh is contraindicated * History of heart failure or thrombosis * Allergic to ultrasound gel * History of spine surgery * Non-English speaker * Currently pregnant or intends to become pregnant during the study

Interventions

DEVICE

Ischemic Preconditioning

DEVICE

Sham Intervention

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Conditions

Low Back PainKnee Osteoarthritis

Locations

Human and Sport Performance Lab

Chicago, Illinois 60608

United States