NCT07003113NARecruiting
Ischemic Preconditioning in Osteoarthritis and Back Pain
University of Illinois at Chicago
Start Date
9/12/2025
Completion Date
12/31/2026
Summary
We are examining the use of restricted blood flow, through full occlusion, on a single thigh for 50 minutes (5 minutes on, 5 minutes off), completed every other day for 2 weeks to improve function in individuals with knee osteoarthritis and low back pain.
Eligibility Criteria
Age Range: 50 years to No maximum
Inclusion Criteria:
* Reported Knee Pain using ACR Criteria
* Reported Back Pain using ODI Criteria \> 12
* Ability to walk for at least 3 minutes without the use of aids
* Ability to provide written informed consent
Exclusion Criteria:
* Younger than 50 years old
* History of Knee or Hip Replacements
* History of steroid injection within the previous 6 months
* Presence of neuromuscular joint condition that affects lower extremity function
* History of blood clots in the leg or any condition in which compression of the thigh is contraindicated
* History of heart failure or thrombosis
* Allergic to ultrasound gel
* History of spine surgery
* Non-English speaker
* Currently pregnant or intends to become pregnant during the study
Interventions
DEVICE
Ischemic Preconditioning
DEVICE
Sham Intervention
Conditions
Low Back PainKnee Osteoarthritis
Locations
Human and Sport Performance Lab
Chicago, Illinois 60608
United States