NCT07006142NARecruiting

Effect of Prolonged Fasting Time on Gastric Residual Volume in Patients Taking GLP1 Receptor Agonists

Mayo Clinic

Start Date

8/1/2025

Completion Date

8/30/2026

Summary

The aim of this study is to determine whether a modified fasting protocol can reduce the potential risk of aspiration for patients currently prescribed GLP1-RAs.

Detailed Description

The overall objective of this project is to identify a reasonable means by which patients on GLP1-RAs can be safely cared for in the perioperative period that can be agreed upon by all groups involved in perioperative patient care. This will be assessed in patients undergoing upper endoscopy specifically since assessment of gastric contents would be minimally invasive for this patient population receiving anesthetic care.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Patients undergoing elective upper endoscopy with gastroenterology team Exclusion Criteria: * Urgent or emergent procedure * Inclusion of colonoscopy or antegrade small bowel enteroscopy in planned procedure * Upper GI barium study performed in past 24 hours. * Gastroparesis * Achalasia * Pancreatitis * Use of outpatient pro-motility medications * Patient refusal * Inability for patient to provide own consent

Interventions

OTHER

Modified Fasting Guidelines

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Conditions

Upper EndoscopyGLP1-R-related Disease

Locations

Mayo Clinic in Rochester

Rochester, Minnesota 55905

United States