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NCT07009210NARecruiting

AI Assisted Personalized Legacy Program (Reflections: My Story) for Patients With Serious Illness

Mayo Clinic

Start Date

8/11/2025

Completion Date

6/30/2027

Summary

The purpose of this study is to determine if it is feasible and acceptable to recruit for and deliver the AI Assisted Personalized Legacy Program intervention to patients with serious illness.

Detailed Description

This study is an investigator-initiated, multi-site Mayo Clinic prospective minimal risk pilot study to determine feasibility and acceptability of an AI Assisted Personalized Legacy Program. The AI Assisted Personalized Legacy Program intervention is a brief, individualized psychotherapy that aims to relieve psycho-emotional and existential distress and improve the experiences of patients whose lives are impacted by serious illness. This therapy offers patients an opportunity to reflect on their life with a trained facilitator and share their thoughts and memories with family and other people in their life. The sessions are recorded and transcribed. The interventionist will work with patients to edit the document and provide a final legacy document for patient to keep and give to loved ones.

Eligibility Criteria

Age Range: 18 years to No maximum

Participant population: Adults with serious illness - defined as a health condition that carries a high risk of mortality Inclusion Criteria for patients: 1. Age ≥18 years 2. English fluency 3. Provide informed consent 4. Ability to complete questionnaire(s) by themselves or with assistance Exclusion Criteria: 1. Other psychological co-morbidities such as untreated schizophrenia, bipolar disease 2. Recent suicide attempt or psychiatric illness severe enough that hospitalization has been necessary in last 6 months 3. Active delirium 4. Advanced dementia 5. Participation in concurrent legacy offerings through the palliative care clinic

Interventions

BEHAVIORAL

AI Assisted Personalized Legacy Program

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Conditions

Serious IllnessExistential Distress

Locations

Mayo Clinic

Phoenix, Arizona 85054

United States

Mayo Clinic

Rochester, Minnesota 55905

United States