NCT07009288NARecruiting
A Study of Time-Restricted Eating in Childhood Cancer Survivors
Memorial Sloan Kettering Cancer Center
Start Date
5/27/2025
Completion Date
5/1/2031
Summary
This study will look at whether motivational sessions (including regular calls with a trained health coach) in combination with time-restricted eating (TRE) is an effective way to achieve weight loss and lower cardiometabolic risk in adult survivors of childhood cancer. The researchers will look at how effective this intervention is compared to the usual approach, which is to review educational materials and measure weight once a month. This study will not provide treatment for any disease or cancer.
Eligibility Criteria
Age Range: 18 years to No maximum
Inclusion Criteria:
* Enrolled in the Childhood Cancer Survivor Study (a cohort of 5+ year survivors of childhood cancer diagnosed at age \< 21 between 1970-1999 at 31 participating institutions in North America)
* Are ≥18 years old
* Self-reported body mass index ≥ 25 kg/m2
* Are not pregnant or do not intend to become pregnant in the next year
* Stable weight over the past 3 months (+/- 10 pounds)
* If on oral medication for insulin resistance (ie, metformin), elevated blood pressure, or dyslipidemia, medication dose must be stable (ie, unchanged \> 3 months)
* Have internet access (can be via smartphone or computer). If neither device is available, the study can loan participants a Wi-Fi enabled device.
Exclusion Criteria:
* Do not reside in the United States
* Do not speak English
* Eating window \< 12 hours per 24-hour day
* On insulin or GLP-1 agonist
* Diagnosis of type 1 diabetes mellitus
* Enrolled in a formal weight management program or other weight loss trial
* History of an eating disorder
Interventions
OTHER
Children's Oncology Group Heart Health Link
OTHER
Monthly weights
OTHER
Fasting
OTHER
Calls
OTHER
Participant Questionnaires
OTHER
Dried blood spot
Conditions
Childhood Cancer Survivors
Locations
Hunter College
New York, New York 10065
United States
Memorial Sloan Kettering Cancer Center
New York, New York 10065
United States
St. Jude Children's Research Hospital (Data Collection Only)
Memphis, Tennessee 38105
United States
Fred Hutchinson Cancer Research Center (Data Collection Only)
Seattle, Washington 98109
United States