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NCT07013435NARecruiting

A Resilience-Based Approach to Improve Long-term Quality of Life in Post-treatment Lymphoma Survivorship

Massachusetts General Hospital

Start Date

10/6/2026

Completion Date

8/1/2030

Summary

The goal of this trial is to learn if a resilience intervention can lead to improvements in lymphoma survivors' quality of life.

Detailed Description

The Stress Management and Relaxation Response Resiliency Program for lymphoma survivors (SMART3RP-Lymphoma) was adapted by researchers at the MGH. This group program seeks to buffer stress and promote psychological resiliency and physical well-being through a variety of mind-body approaches, such as imagery, relaxation, and yoga, cognitive behavioral strategies, and positive psychology tools. The main questions it aims to answer are: * Will survivors randomized to SMART3RP-Lymphoma demonstrate greater improvements in quality of life when compared to survivors randomized to a Health Education Program? * Will improvements in resiliency lead to improvements in quality of life? To answer these questions, researchers will compare a resilience intervention tailored to the needs of lymphoma survivors (SMART3RP-Lymphoma) to a Health Education Program to see how they affect quality of life of lymphoma survivors. Participants will: * Fill out 4 surveys across 12 months * Participate in 8 weekly, virtual group sessions * Submit hair cortisol samples

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * English or Spanish speaking adults (18+ at time of enrollment) * Within 1-5 years of completing active treatment for lymphoma (includes surgery, chemotherapy, immunotherapy, radiation therapy, or other); individuals may be on maintenance treatment. Exclusion Criteria: * Active psychiatric, medical concern or cognitive comorbidity as determined by the site PI or treating clinician

Interventions

OTHER

Health Education Program

OTHER

SMART3RP-Lymphoma

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Conditions

Lymphoma

Locations

Mass General Hospital

Boston, Massachusetts 02114

United States

Huntsman Cancer Institute

Salt Lake City, Utah 84112

United States