Prospective Registry of Patients Undergoing Cardiac CT With NAEOTOM Alpha PCD-CT Before TAVI Procedure
Start Date
6/1/2024
Completion Date
5/30/2030
Summary
The clinical and demographic characteristics of patients undergoing transcatheter aortic valve implantation (TAVI) pose unique challenges for coronary computed tomography (CT) imaging, as this patient population is mainly composed of elderly, frail individuals with severe aortic stenosis, multiple comorbidities, high prevalence of heavily calcified coronary artery disease (CAD) and revascularized coronary arteries. Such vulnerable patients could benefit from a more precise assessment and characterization of their CAD with ultra-high resolution (UHR) photon-counting detector (PCD) CT that would potentially avoid the need for pre-implantation invasive coronary angiography (ICA). This international multicenter prospective registry study aims to investigate the feasibility and diagnostic accuracy of PCD-CT in the assessment of CAD in the high-risk population of patients undergoing TAVI, as compared to ICA.
Eligibility Criteria
Age Range: 18 years to No maximum
Interventions
Ultra-High Resolution Photon Counting Detector Coronary Computed Tomography Angiography
Conditions
Locations
Medical University of South Carolina
Charleston, South Carolina 29425
United States
Albert-Ludwigs-Universität Freiburg
Freiburg im Breisgau, 79098
Germany
University Medical Center Mainz
Mainz, 55116
Germany
Universitätsklinikum Tübingen
Tübingen, 2669
Germany
Semmelweis University
Budapest,
Hungary
Maastricht University
Maastricht, 6211
Netherlands
University Hospital of Zürich
Zurich, 8091
Switzerland