Ovarian PRP Injections for Improved Embryo Quality Using Embryo Quality Score

Summary

Patients will have ovarian PRP treatments and embryo development will be observed using time-lapse imaging and AI software.

Detailed Description

. oPRP Treatment \& Second IVF Cycle (Study Cycle) * Following the first IVF cycle, patients will undergo their first oPRP injection: * Timing: 1-2 weeks after the onset of the next menstrual cycle. * Procedure: Under IV sedation, a patient's autologous PRP will be prepared and injected directly into both ovaries under transvaginal ultrasound guidance. * Second IVF Cycle (oPRP Study Cycle) * The same ovarian stimulation protocol will be used for consistency. * A second oPRP injection will be performed on stimulation days 2-5 to enhance folliculogenesis. * Ovulation will be triggered at the same follicular size thresholds, and oocyte retrieval will follow identical protocols. * Fertilization methodology will be identical to the first cycle unless no fertilization is identified in the first cycle. * Embryo Development Analysis: Up to 15 embryos will be cultured in the AI incubator, where time-lapse imaging will track their morphokinetics, and AI-based analysis will assess embryo viability and implantation potential.

Eligibility Criteria

Interventions