Back to Trials
NCT07029243NARecruiting

Prehab and Creatine/Whey Supplementation in Frailty Among Patients With Cirrhosis

University of California, San Francisco

Start Date

4/15/2026

Completion Date

12/1/2026

Summary

Frailty and muscle health are important for patients with chronic liver disease. This study looks at the use of a digital prehabilitation app (HEAL-ME) plus creatine and whey protein combination supplementation on maintaining muscle health in patients with liver disease. The investigators anticipate that this combination of supplementation and nutrition/exercise prehabilitation app will maintain muscle health in patients with liver disease.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Confirmed diagnosis of cirrhosis by ICD-10 code, liver biopsy, abdominal imaging, or transient elastography * Access to digital device and internet at home * Ability to provide written informed consent before any study-related activities * Ability to remain in study for at least 3 months Exclusion Criteria: * Allergy to milk protein * On hemodialysis * No English language proficiency * Presence of condition or abnormality that in opinion of the Investigator will compromise safety of the patient or quality of the data * Concomitant severe underlying systemic illness that in the opinion of the Investigator would interfere with completion of study * Pregnant, breastfeeding, or intention of becoming pregnant during study time frame

Interventions

BEHAVIORAL

HEAL-ME digital app

DIETARY_SUPPLEMENT

Creatine supplementation

DIETARY_SUPPLEMENT

Whey protein supplementation

DIETARY_SUPPLEMENT

Placebo

Interested in This Trial?

Contact the trial locations directly using the information below to learn more about enrollment.

Expressing interest lets you review the study and consent before we connect you with the research site.

Conditions

CirrhosisFrailtySarcopenia

Locations

University of California San Francisco

San Francisco, California 94143

United States