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NCT07044505NARecruiting

Molecular and Cellular Profiling of Uterine Lavage Collected During Gynecologic Surgery

Stanford University

Start Date

9/19/2025

Completion Date

12/1/2026

Summary

This study is a designed as a to test the clinical and technical feasibility of using this novel uterine lavage collection catheter to collected UL samples from up to 50 individuals undergoing gynecologic surgery and to describe the cellular composition of these samples. In order to do this, it is a prospective consecutively-enrolled cohort of 50 participants, all of who will receive the intervention of uterine lavage collection.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Undergoing gynecologic surgery with Stanford Healthcare * Intact uterus and cervix * At least one intact fallopian tube and ovary (on the same side) * Aged 18 years or older * Ability to understand and the willingness to provide written informed consent. Exclusion Criteria: * Known endometrial or cervical cancer or endometrial or cervical intraepithelial neoplasia * Status post bilateral salpingectomy or tubal ligation * Lack of consenting capacity * Positive preoperative pregnancy test * Active uterine bleeding (i.e. menses, etc.) * Intrauterine device in place * Non-English speaking (requires interpretor)

Interventions

PROCEDURE

Uterine Lavage

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Conditions

Gynecologic CancerGynecologic DiseaseGynecological SurgeryUterine Cancer

Locations

Stanford University

Palo Alto, California 94304

United States