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NCT07044726PHASE4RecruitingAccepts Healthy Volunteers

Betadine vs Sterile Water for Periurethral Preparation

University of Louisville

Start Date

6/30/2025

Completion Date

5/21/2028

Summary

The purpose of this study is to determine whether cleaning of the urethra, or external opening to the bladder, with sterile water (water that has been treated to remove bacteria and living organisms) vs Betadine also known as Povidone-Iodine (a medical grade cleaning solution) changes the rates of bacteria in the urine after a temporary catheter, or draining tube, is placed into the bladder. Chemical antiseptics, including Betadine, are the current standard of care. An additional goal of this study is to determine whether cleaning of the urethra, or external opening to the bladder, with sterile water vs betadine changes the amount of discomfort or pain patients experience with placement of a temporary catheter, or draining tube, in the bladder.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Aged 18+ * Patient undergoing in office straight catherization Exclusion Criteria: * History of culture proven recurrent urinary tract infection (2 in any 6-month period or 3 in any 12-month period) * Urine Analysis with +Nitrites * Catherization for any reason in the last 4 weeks * History of Iodine allergy * Patients unable to speak English * Patient does not have the capacity to consent * 2-3rd trimester pregnancy

Interventions

DRUG

Povidone-Iodine

DRUG

Sterile water

Interested in This Trial?

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Conditions

CatherizationUrinary Tract Infection Bacterial

Locations

UofL Physicians - Urogynecology Springs Urogynecology Office

Louisville, Kentucky 40205

United States

UofL Health - Urogynecology Mary & Elizabeth Hospital, Medical Plaza 3

Louisville, Kentucky 40215

United States