HCMR Re-Imaging Study
Start Date
3/30/2026
Completion Date
7/1/2027
Summary
This study aims to learn what might predict heart problems (like sudden death from a fast heart rhythm or heart failure) in people with a genetic condition called hypertrophic cardiomyopathy (HCM). HCM causes the heart muscle to become thick, which can make the heart stiff and harder to work properly. It can also affect the heart's electrical system. This study is looking to enroll patients that were previously part of a research project called "HCMR - Novel Predictors of Outcome in Hypertrophic Cardiomyopathy." The results of that study are still being reviewed, but they might show that people who had a substance called Gadolinium (MRI contrast or dye) collected in their heart muscle may have a higher risk for heart problems, including sudden cardiac death. This is called "late gadolinium enhancement" (LGE). This study is aiming to do follow-up imaging on those patients to better understand how LGE affects people with HCM.
Eligibility Criteria
Age Range: 18 years to 65 years
Interventions
None - observational study
Conditions
Locations
Northwestern
Evanston, Illinois 60208
United States
Brigham & Women's Hospital
Boston, Massachusetts 02115
United States
Tufts Medical Center
Medford, Massachusetts 02155
United States
University of Michigan
Ann Arbor, Michigan 48109
United States
Cleveland Clinic
Cleveland, Ohio 44195
United States
University of Virginia
Charlottesville, Virginia 22903
United States
University Hospitals Birmingham NHS Foundation Trust
Birmingham, B15 2GW
United Kingdom
London Chest Hospital
London, E2 9JX
United Kingdom