NCT07054944Recruiting
Tumor-Lymph Node Mapping
University of Rochester
Start Date
4/13/2026
Completion Date
7/30/2028
Summary
The purpose of this study is to assess the feasibility and safety of ICG-guided intraoperative lymphography for detecting sentinel lymph nodes (SLN) in pediatric patients with solid tumors who require retroperitoneal lymph node dissection/sampling. This trial is a single-site cross-sectional study. The injection of ICG directly into lymphatics draining the primary tumor will take place at the time of operation after the patient is under anesthesia.
Eligibility Criteria
Age Range: No minimum to 17 years
Inclusion Criteria:
* Any pediatric patient (under the age of 18 years) being treated at the University of Rochester Medical Center, Department of Surgery.
* Diagnosed with pediatric solid tumor
* Scheduled to undergo lymph node sampling as part of their clinical management.
Exclusion Criteria:
* Subjects with a history of iodide allergies.
* Inability or unwillingness of research participant or parent/legal guardian to give written informed consent.
* Currently pregnant.
* Infants under 650 grams.
* Patients with extensive prior surgery at the primary site or nodal basin expected to affect the lymphatic drainage.
Interventions
DIAGNOSTIC_TEST
ICG (Indocyanine Green)
Conditions
Pediatric Solid TumorsRhabdomyosarcomaSarcomaGerm Cell Tumor
Locations
University of Rochester Medical Center
Rochester, New York 14642
United States