NCT07058064NARecruiting
WATCH (Wearable Artificial inTelligence for Cardiac Function and Health Monitoring)
Mayo Clinic
Start Date
7/18/2025
Completion Date
6/29/2029
Summary
The purpose of this study is to find a cost effective cardiovascular (CV) surveillance of cancer survivors over long periods of time to prevent the risk of progression of heart failure (HF) and related morbidity and mortality. Mobile device-based artificial intelligence (AI)-electrocardiogram (ECG) can reliably detect cardiac dysfunction in lymphoma and sarcoma survivors and smart watch based surveillance for cardiotoxicity is feasible and reliable.
Eligibility Criteria
Age Range: 18 years to No maximum
Inclusion Criteria:
* ability to understand study procedures and being willing to comply with them for the entire study length
* diagnosis of lymphoma or sarcoma with new start or 1 year after completion of anthracycline therapy
Exclusion Criteria:
* LVEF \<50% at baseline, or prior confirmed history of heart failure, persistent atrial fibrillation, left bundle branch block, or paced rhythm
* Unwilling or unable to give written informed consent
* Participants who have opted out of the Minnesota Research Authorization
Interventions
PROCEDURE
Electrocardiogram
PROCEDURE
Echocardiogram
PROCEDURE
LVEF echocardiogram
OTHER
Apple Watch
PROCEDURE
Biospecimen collection
OTHER
Questionnaires
OTHER
Cardio-pulmonary exercise test
OTHER
6 minute walk test
OTHER
Grip strength test
Conditions
LymphomaSarcoma
Locations
Mayo Clinic in Rochester
Rochester, Minnesota 55905
United States