Ropivacaine and Fentanyl for Labor Epidural Initiation
Start Date
10/24/2025
Completion Date
7/31/2026
Summary
This study is being done to determine the most effective dose of medicine to use to initially provide effective pain relief within the first 30 minutes of receiving an epidural for pain labor during labor. The study team will also study any side effects related to the epidural medication and patients' satisfaction with the quality of pain relief after receiving the epidural.
Detailed Description
We aim to perform a prospective observational study in a single cohort of 50 patients receiving a dural-puncture epidural technique for labor analgesia. We will use a biased-coin up-down allocation methodology to quantify the volume of a combined epidural 0.1% ropivacaine and 2 mcg/ml fentanyl regimen that achieves effective analgesia in 90% of patients experiencing active labor who receive a dural-puncture epidural technique for labor analgesia.
Eligibility Criteria
Age Range: 18 years to No maximum
Interventions
Ropivacaine + Fentanyl
Conditions
Locations
University of California, San Francisco
San Francisco, California 94158
United States