NCT07103993NARecruitingAccepts Healthy Volunteers
Food Intake and Thermogenesis in High Spinal Cord Injury
University of Miami
Start Date
3/13/2026
Completion Date
12/31/2027
Summary
The purpose of this research is to determine the effects of food on cardiovascular and metabolic health in men with and without spinal cord injury (SCI).
Eligibility Criteria
Age Range: 18 years to 65 years
Inclusion Criteria:
SCI and Controls
* Men
* Physically inactive (\<150 minutes per week of moderate-vigorous activity intensity for the preceding 3 months)
* Weight stable: body mass ±3 kilograms (kg) for past 3 months
SCI Only
* Chronic SCI (≥ 1-year post-injury)
* Motor-complete SCI American Spinal Injury Association Impairment Scale (AIS) A and B
* T6 injuries and above that can independently feed themselves
Exclusion Criteria:
SCI and Controls
* Uncompensated thyroid disease
* Diabetes
* Swallowing or gastrointestinal pathologies
* Allergies or aversions to foods/ingredients
* Prescribed prokinetic, antipsychotic, or anti-obesity agents
SCI Only
* Incomplete SCI AIS C or D
* Ventilator-dependent
Interventions
OTHER
Low meal condition
OTHER
Moderate meal condition
OTHER
High meal condition
OTHER
Ad-libitum control condition
Conditions
SCI - Spinal Cord Injury
Locations
University of Miami - Miami Project to Cure Paralysis
Miami, Florida 33136
United States