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NCT07115212NARecruiting

Bromelain for Post-surgery Facial Swelling

Mohamed Bazina

Start Date

9/8/2025

Completion Date

5/1/2028

Summary

The goal of this clinical trial is to learn if Bromelain Supplement works to decrease the amount of swelling or the amount of time swelling is present following jaw surgery. It will also learn about the safety of Bromelain supplement. The main questions it aims to answer are: Does Bromelain decrease facial swelling following orthognathic, or jaw, surgery? Does Bromelain supplement decrease the amount of time that patients are swollen following orthognathic, or jaw, surgery? Participants will: Take Bromelain supplement once daily for 9 days total. Take 2 days before surgery and 7 days following surgery. Keep a log of when the bromelain supplement is taken as well as another other medications. Visit the clinic with pre and post surgical protocol

Eligibility Criteria

Age Range: 18 years to 65 years

Inclusion Criteria: * undergoing orthognathic surgery Exclusion Criteria: * craniofacial anomalies * incomplete patient data * systemic disease that could affect healing * allergy to latex or pineapple * under 18 years of age * non english speaking

Interventions

DIETARY_SUPPLEMENT

Bromelain

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Conditions

Malocclusion

Locations

University of Kentucky

Lexington, Kentucky 40356

United States