Skip to main content
Back to Trials
NCT07134426NARecruitingAccepts Healthy Volunteers

Vaped Phenanthrene

University of Minnesota

Start Date

9/1/2026

Completion Date

6/30/2028

Summary

Some people who used to smoke cigarettes continue to be at higher risk of developing lung cancer, even years after quitting. This study will look to see if a specific chemical, phenanthrene, is broken down in the lungs of former smokers through more harmful pathways than never-smokers. If former smokers break down chemicals that enter their lungs through more harmful pathways this might be putting them at higher risk for developing lung cancer even though they quit smoking. This information may help find better ways to prevent or treat cancer in the future. This study is under an IND, but the drug is not being studied; instead, it is being used as a marker for drug metabolism.

Eligibility Criteria

Age Range: 21 years to No maximum

Inclusion Criteria: * \> 21 years of age * In good physical \& mental health * In stable physical \& mental health * Have tried vaping * Former daily cigarette smokers who quit 1-20 year ago * Non-smokers who have not used tobacco or nicotine products Exclusion Criteria: * Has any respiratory disease (ex - asthma, COPD, etc...) * Has/had high blood pressure * Has/had liver disease * Has/had cancer * Has experience negative effects when vaped previously * Pregnant or nursing

Interventions

OTHER

D10-phenanthrene

Interested in This Trial?

Contact the trial locations directly using the information below to learn more about enrollment.

Expressing interest lets you review the study and consent before we connect you with the research site.

Conditions

Former SmokerNon-Smoker

Locations

University of Minnesota

Minneapolis, Minnesota 55455

United States