Extended Intervention for Tobacco Use (EXIT) for People Experiencing Homelessness
Start Date
11/14/2025
Completion Date
6/30/2027
Summary
This study is investigating tobacco use and providing tobacco treatment among people experiencing homelessness in California, in San Francisco and Los Angeles.
Detailed Description
PRIMARY OBJECTIVES: I. Biochemically verified 7-day point prevalence tobacco abstinence at 6-months follow-up. II. Use expired carbon monoxide (CO) to confirm self-reports of abstinence using a cut-off of CO ≤5 parts per million (ppm). SECONDARY OBJECTIVES: I. Biochemically-verified 7-day point prevalence tobacco abstinence at 3-months follow-up. II. Measured at 6-months follow-up, a total number of expired carbon monoxide (CO-negative samples). III. Measured at 6-months follow-up, longest duration of abstinence (i.e., total number of uninterrupted days abstinent), proportion with 50% reduction in expired CO for those who do not quit smoking. IV. Use expired CO to confirm self-reports of abstinence using a cut-off of CO ≤5 ppm. OUTLINE: Participants will be randomized to one of two groups: * Intervention group receives 6 months of pharmacist consultation, monthly delivery of nicotine replacement therapy, and telephone wellness coaching. * Control group receives pharmacist consultation and monthly delivery of nicotine replacement therapy for 3 months. Participants will be followed up at 1, 3 and 6 months.
Eligibility Criteria
Age Range: 18 years to No maximum
Interventions
Nicotine Replacement Therapy (NRT)
Wellness Coaching
Conditions
Locations
University of California, San Francisco
San Francisco, California 94143
United States