Back to Trials
NCT07159750Recruiting

Real-world Prospective Study on the Use of Anti-CGRP Drugs in Migraine

Hospital Universitari Vall d'Hebron Research Institute

Start Date

1/2/2024

Completion Date

1/1/2026

Summary

The goal of this observational study is to evaluate clinical differences in patients who received preventive treatment with medication targeting calcitonin gene-related peptide (CGRP) or its receptor: monoclonal antibodies (erenumab, galcanezumab, fremanezumab, eptinezumab) or gepants (rimegepant, atogepant) during a 2-year period observation phase.

Detailed Description

It is a 2-year, multicenter observational study. Patients who meet reimbursement criteria according to local regulations and willing to participate in the study will be included. Monoclonal antibodies (erenumab, galcanezumab, fremanezumab, eptinezumab) or gepants (rimegepant, atogepant) will be started and baseline assessment will be conducted. There will be visits every 6 months to assess effectiveness, side-effects, PROMs, and elegibility to continue with the study drug. The observation of patients will last 2 years.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Migraine diagnosis according to ICHD-III. * Prescription of erenumab, galcanezumab, fremanezumab, eptinezumab, atogepant or rimegepant according to prescriptor criteria and reimbursement criteria according to local regulations. * Signature of informed consent. Exclusion Criteria: * Presence of headache different from migraine. * Active severe psychiatric condition or cognitive impairment which may affect the ability to consent patient's participation in the study.

Interventions

DRUG

CGRP antibody or gepant

Interested in This Trial?

Contact the trial locations directly using the information below to learn more about enrollment.

Expressing interest lets you review the study and consent before we connect you with the research site.

Conditions

MigraineEpisodic MigraineChronic Migraine, Headache

Locations

University of Miami, Miller School of Medicine

Miami, Florida 33136

United States

FLENI

Buenos Aires,

Argentina

Pontificia Universidad Católica de Chile

Santiago,

Chile

Neuromedica

Medellín,

Colombia

Special Hospital for Orthopedics and Rehabilitation "Martin Horvat" Rovinj-Rovigno

Rovinj,

Croatia

Charité Universitätsmedizin Berlin

Berlin,

Germany

LMU University Hospital

München,

Germany

University of L'Aquila

L’Aquila,

Italy

University of Modena and Reggio Emilia

Modena,

Italy

National Neurological Institute C. Mondino Foundation

Pavia,

Italy

IRCCS San Raffaele

Roma,

Italy

Universiti Putra Malaysia

Serdang, Selangor

Malaysia

Neuroclinic Norway

Lillestrøm,

Norway

Wrocław Medical University

Wroclaw,

Poland

Hospital Santa Maria Lisbon

Lisbon,

Portugal

Germans Trias i Pujol Hospital

Badalona, Barcelona

Spain

Vall d'Hebron University Hospital

Barcelona, Barcelona 08035

Spain

Hospital Universitari de Bellvitge

L'Hospitalet de Llobregat, Barcelona

Spain

Fundació Sanitària Mollet

Mollet del Vallès, Barcelona

Spain

Hospital de Viladecans

Viladecans, Barcelona

Spain

Hospital General Universitario de Albacete

Albacete,

Spain

Fundación Jiménez Díaz

Madrid,

Spain

Hospital Universitario Gregorio Marañón

Madrid,

Spain

La Paz University Hospital

Madrid,

Spain

Hospital Clínico Universitario Lozano Blesa

Zaragoza,

Spain

Mersin University

Mersin,

Turkey (Türkiye)