NCT07182240NARecruiting
Pilot Study of Line-Field Confocal Optical Coherence Tomography for Detection of Mohs Micrographic Surgery Margins of Basal Cell Carcinomas
Roswell Park Cancer Institute
Start Date
12/22/2025
Completion Date
6/22/2027
Summary
To assess the feasibility and provide information on the utility of noninvasive line field confocal optical coherence tomography (LC-OCT) for the presurgical assessment of Mohs micrographic surgery sites in patients undergoing removal of cutaneous basal cell carcinomas (BCC).
Eligibility Criteria
Age Range: 18 years to No maximum
Inclusion Criteria:
* Age ≥ 18 years
* Participant must understand the investigational nature of this study and provide written consent prior to receiving any study-related procedure.
* Participant must be clinically eligible for Mohs surgery as determined by their referring dermatologist and the Mohs surgeon.
* The participant must have a BCC with superficial histology or a BCC with multiple histological features that also include superficial histology, which is appropriate for Mohs surgery.
Exclusion Criteria:
* Known or reported allergy to mineral oil, the optical agent used during imaging.
* Uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements.
* . Any condition which in the investigator's opinion deems the subject an unsuitable candidate to undergo imaging procedure.
* Unwilling or unable to follow protocol requirements
Interventions
DEVICE
LC-OCT Imaging
Conditions
Basal Cell Carcinoma
Locations
Roswell Park Comprehensive Cancer Center
Buffalo, New York 14263
United States