NCT07186192PHASE3RecruitingAccepts Healthy Volunteers
Digital Health Intervention for Self-Management and Telemonitoring in Chimeric Antigen Receptor (CAR-T) Therapy
City of Hope Medical Center
Start Date
1/14/2026
Completion Date
3/29/2029
Summary
The overall purpose of this randomized control trial (RCT) is to determine the clinical effect of a multilevel, RPM-enhanced intervention during and after completion of outpatient CAR-T therapy in 190 patients and their family caregivers (FCGs).
Eligibility Criteria
Age Range: 18 years to No maximum
Inclusion Criteria:
Patient Inclusion Criteria Informed Consent and Willingness to Participate
1. Documented informed consent of the participant and/or legally authorized representative Age and Language Criteria
2. Age ≥ 18 years old at the time of enrollment
3. Ability to read and understand English or Spanish for Questionnaires Nature of Illness and Treatment Related Criteria
4. Relapsed or refractory hematologic malignancy
5. Scheduled to receive outpatient standard of care (SOC) CAR-T therapy
6. Has a FCG committed to living with the patient for the duration of the study
Family Caregiver Inclusion Criteria Informed Consent and Willingness to Participate
1. Documented informed consent of the participant and/or legally authorized representative Age and Language Criteria
2. Age ≥ 18 years old at the time of enrollment
3. Ability to read and understand English or Spanish for Questionnaires Nature of Illness and Treatment Related Criteria
4. Family member or friend identified by the patient and defined as a person who knows the patient well and is involved in the patient's medical care
Exclusion Criteria 1. An employee who is under the direct/indirect supervision of the PI/ a co-investigator/ the study manager 2. A direct study team member
\-
Interventions
OTHER
Educational Intervention
PROCEDURE
Health Telemonitoring
OTHER
Questionnaire Administration
OTHER
Best Practice
Conditions
Hematologic Malignancies
Locations
City of Hope Medical Center
Duarte, California 91010
United States