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NCT07195175PHASE1RecruitingAccepts Healthy Volunteers

Study of MAR002 in Healthy Men

Marea Therapeutics

Start Date

8/11/2025

Completion Date

7/1/2026

Summary

Evaluate the safety and tolerability of subcutaneous (SC) administration of MAR002 in healthy men

Eligibility Criteria

Age Range: 18 years to 40 years

Inclusion Criteria: 1. Willingness to provide written informed consent 2. Age 18 to 40 3. Weight 55 to 95 kg 4. Body mass index (BMI) 18 to 30 kg/m2 5. Healthy men Exclusion Criteria: 1. History of hypersensitivity to monoclonal antibodies or study drug 2. Participation in any other investigational drug study 3. History of cancer 4. Recent acute illness 5. Positive test for HIV, hepatitis B/C 6. History of substance abuse or nicotine use 7. Recent blood donation 8. History of pituitary disorder 9. Any condition that prevents the participant from complying with study procedures

Interventions

DRUG

MAR002

DRUG

Placebo

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Conditions

Acromegaly

Locations

Marea Site

Tempe, Arizona 85283

United States