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NCT07209176NARecruiting

Physician- and Patient-based Barriers to NGS Testing

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Start Date

1/6/2026

Completion Date

9/6/2027

Summary

The goal of this study is to improve next-generation sequencing (NGS) testing rates at Johns Hopkins in patients with metastatic prostate cancer. Investigators believe by targeting two barriers, provider-level and patient-level, will improve the testing rate of NGS at Johns Hopkins.

Detailed Description

Next-generation sequencing is recommended by national guidelines in metastatic prostate cancer to inform prognosis, treatment decisions, and eligibility for clinical trials. However, rates are low nationally and around 50-60% at Johns Hopkins. Analysis found that older patients and patients who are not married are less likely to have testing performed. The goals and objectives of this proposed clinical trial are to improve NGS testing rates at Johns Hopkins using a multidisciplinary approach to improve the care of patients living with metastatic prostate cancer and reduce disparities. The hypothesis is that this initiative, which targets two barriers (provider-level and patient-level), will lead to higher rates of NGS ordering at Johns Hopkins.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * men diagnosed with metastatic prostate cancer * seen by Johns Hopkins Medical Oncology as a new patient visit between January 1, 2025 and December 31, 2026 Exclusion Criteria: \- Patients who have already had NGS testing performed.

Interventions

OTHER

Provider-level and patient education at end of study

OTHER

Provider-level and patient-level

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Conditions

Metastatic Prostate Cancer

Locations

Johns Hopkins Sidney Kimmel Comprehensive Cancer Center

Baltimore, Maryland 21205

United States