Enhanced Valves Interventions and Safe AI Generated End Results
Start Date
5/1/2024
Completion Date
5/1/2029
Summary
This non-interventional study aims to use artificial intelligence to improve the prediction of transcatheter heart valve interventions and optimize patient outcomes. It is based on the analysis of retrospective data from various specialized centers worldwide.
Detailed Description
The ENVISAGE study is a non-interventional, retrospective research study designed to validate an artificial intelligence (AI)-based framework for the automated analysis of cardiac imaging data, including multi-slice cardiac computed tomography (CT) and transesophageal echocardiography (TEE). The primary objective is to predict the success of transcatheter heart valve interventions, including aortic, mitral, and tricuspid valve interventions (TAVI, TMVI, M-TEER, T-TEER). The AI framework developed in this study will rely on deep learning algorithms, particularly convolutional neural networks (CNNs) and other advanced models, to automatically segment critical anatomical structures and perform accurate measurements of these structures from CT and TEE images. These measurements will then be combined with pre-interventional clinical data to optimize patient selection and intervention planning, as well as to predict surgical outcomes with high accuracy. AI will also aim to reduce human error and inter-observer variability in the interpretation of cardiac images, which could significantly improve clinical outcomes.
Eligibility Criteria
Age Range: 18 years to No maximum
Interventions
Medical imaging analysis via artificial intelligence algorithms
Conditions
Locations
Montefiore Medical Center New York
New York, New York 10467
United States
Montreal Heart Institute, 5000 Rue Bélanger, Montréal
Montreal, Quebec H1T 1C8
Canada
St Michael's Hospital Toronto
Toronto,
Canada
St Paul's Hospital Vancouver
Vancouver,
Canada
Centre Hospitalier Universitaire (CHU) de Bordeaux, 12 rue Dubernat 33404 Talence cedex
Bourdeaux, 33404
France
CHU Lille
Lille,
France
CHU Marseille
Marseille,
France
Centre Cardiologique du Nord Paris
Paris,
France
Institut Cardiovasculaire Paris-Sud Paris
Paris,
France
Centre Hospitalier Universitaire Rennes
Rennes,
France
Clinque Pasteur Toulouse - France
Toulouse,
France
University Medical Center Hamburg-Eppendorf
Hamburg,
Germany
Heart Valve Center Mainz
Mainz,
Germany
Istituto Clinico Città di Brescia
Brescia,
Italy
San Raffaele Heart Valve Center Milan
Milan,
Italy