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NCT07216599NARecruiting

Photoacoustic Imaging of Foot Wound

State University of New York at Buffalo

Start Date

10/28/2025

Completion Date

12/31/2026

Summary

This pilot device trial aims to test the feasibility of using photoacoustic images to monitor tissue perfusion and to guide post-surgical wound treatment. Through this pilot study, the investigators will test the feasibility, identify any practical issues, and acquire essential information (e.g., drop-off rate, variation in wound healing rate) to guide future large-scale studies.

Detailed Description

This pilot device trial aims to test the feasibility of using photoacoustic images to monitor tissue perfusion and to guide post-surgical wound treatment. Through this pilot study, the investigators will test the feasibility, identify any practical issues, and acquire essential information (e.g., drop-off rate, variation in wound healing rate) to guide future large scale studies. For recruited patients, wound care will be guided by both photoacoustic imaging and Kent imaging, a multi-spectral imaging technique for tissue oxygenation mapping. None of the techniques is currently used in the clinic as standard care.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Patients with a chronic wound on the foot that is presumed to be due to arterial insufficiency. Exclusion Criteria: * Patients with a massive deep tissue infection. * Patients with preexisting skin conditions, such as melanoma, psoriasis, in areas close to the wound(s). * Noncompliant patients who do not adhere to care plans. * Pregnant women. * Adults unable to consent.

Interventions

DEVICE

Photoacoustic imaging and multispectral imaging

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Conditions

Foot Ulcer

Locations

UBMD Vascular Surgery

Buffalo, New York 14221

United States