Study to Assess the Adverse Events of Oral ABBV-932 in Adult Participants With Depressive Episodes Associated With Bipolar I or II Disorder
Start Date
9/30/2025
Completion Date
4/1/2027
Summary
Bipolar disorder is a severe chronic mood disorder that affects up to 4% of the adult population in the United States. The purpose of this study is to assess how safe and effective ABBV-932 is in treating participants with depressive episodes associated with bipolar I or II disorder. ABBV-932 is an investigational drug being developed for the treatment of depressive episodes in adult participants with bipolar I or II disorder. Participants with bipolar I or II disorder who are currently experiencing a depressive episode will enter the study and be treated with open-label ABBV-932. Approximately 200 adult participants with bipolar I or II disorder will be enrolled in approximately 50 sites in the United States and Puerto Rico. Participants will receive oral capsules of ABBV-932 for a 26-week treatment period. The treatment period will be followed by a safety follow-up (SFU) period of 30 days. There may be higher treatment burden for participants in this trial compared to their standard of care. Participants will attend regularly scheduled visits during the study at a hospital or clinic. The effect of the treatment will be checked by medical assessments, blood tests, checking for side effects and completing questionnaires.
Eligibility Criteria
Age Range: 18 years to 65 years
Interventions
ABBV-932
Conditions
Locations
Ima Clinical Research Phoenix (Alea) /ID# 278047
Phoenix, Arizona 85012
United States
Advanced Research Center /ID# 273474
Anaheim, California 92805
United States
Axiom Research /ID# 273482
Colton, California 92324
United States
Collaborative Neuroscience Research - Garden Grove /ID# 273492
Garden Grove, California 92845
United States
Sun Valley Research Center /ID# 273472
Imperial, California 92251
United States
Synergy San Diego /ID# 278340
Lemon Grove, California 91945
United States
Alliance for Research Alliance for Wellness /ID# 273477
Long Beach, California 90807
United States
Nrc Research Institute - Los Angeles /ID# 278450
Los Angeles, California 90015
United States
Excell Research /ID# 273483
Oceanside, California 92056
United States
Inland Psychiatric Medical Group /ID# 273471
Temecula, California 92591
United States
Sunwise Clinical Research /ID# 278165
Walnut Creek, California 94596
United States
Connecticut Clinical Research - Cromwell /ID# 278116
Cromwell, Connecticut 06416
United States
Clinical Neuroscience Solutions Healthcare - Jacksonville /ID# 278332
Jacksonville, Florida 32256
United States
GMI Florida - Central Miami Medical Institute /ID# 273486
Miami, Florida 33125
United States
Allied Biomedical Res Inst Inc /ID# 273476
Miami, Florida 33155
United States
Floridian Clinical Research - Miami Lakes /ID# 279379
Miami Lakes, Florida 33016
United States
K2 Medical Research - Orlando - South Orlando Avenue /ID# 273487
Orlando, Florida 32751
United States
Apg Research /ID# 278439
Orlando, Florida 32803
United States
Segal Trials - West Broward Outpatient Research Site /ID# 273496
Tamarac, Florida 33319-4985
United States
Health Synergy Clinical Research /ID# 279384
West Palm Beach, Florida 33407
United States
Trialmed /ID# 278046
Atlanta, Georgia 30328
United States
Atlanta Center for Medical Research /ID# 278827
Atlanta, Georgia 30331
United States
Revive Research Institute - Elgin /ID# 279756
Elgin, Illinois 60123
United States
Benchmark Research /ID# 273490
Shreveport, Louisiana 71101
United States
Pharmasite Research, Inc. /ID# 279163
Baltimore, Maryland 21208
United States
Elixia - Springfield /ID# 278446
Springfield, Massachusetts 01103
United States
MSB Neuroscience /ID# 278168
Jackson, Mississippi 39216-4643
United States
Arch Clinical Trials /ID# 273481
St Louis, Missouri 63125
United States
Alivation Research /ID# 279464
Lincoln, Nebraska 68526
United States
Ima Clinical Research Las Vegas (SMO/Network/Consortium) /ID# 278054
Las Vegas, Nevada 89102
United States
Redbird Research /ID# 279475
Las Vegas, Nevada 89119
United States
Bio Behavioral Health /ID# 273478
Toms River, New Jersey 08755
United States
Integrative Clinical Trials /ID# 278040
Brooklyn, New York 11229
United States
Neurobehavioral Research /ID# 273470
Cedarhurst, New York 11516
United States
Ima Clinical Research - Manhattan /ID# 278941
New York, New York 10036
United States
New Hope Clinical Research - Inpatient unit /ID# 273468
Charlotte, North Carolina 28211
United States
Quest Therapeutics of Avon Lake /ID# 273484
Avon Lake, Ohio 44012
United States
OSU Psychiatry Department /ID# 273495
Columbus, Ohio 43210
United States
Sooner Clinical Research /ID# 273491
Oklahoma City, Oklahoma 73116
United States
Summit Research Network - Portland - Northwest Vaughn Street /ID# 278084
Portland, Oregon 97210
United States
Lehigh Center for Clinical Research /ID# 273466
Allentown, Pennsylvania 18103
United States
FutureSearch Trials of Dallas /ID# 273473
Dallas, Texas 75231
United States
Epic Medical Research - DeSoto /ID# 278045
DeSoto, Texas 75115
United States
Perceptive Pharma Research /ID# 273485
Richmond, Texas 77407
United States
Family Psychiatry Of The Woodlands /ID# 278050
The Woodlands, Texas 77381
United States
Northwest Clinical Research Center /ID# 273480
Bellevue, Washington 98007
United States
Core Clinical Research /ID# 273498
Everett, Washington 98201
United States
Inspira Clinical Research /ID# 274670
San Juan, 00918-3014
Puerto Rico
BDH Research /ID# 274677
San Juan, 00927
Puerto Rico