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NCT07220655NARecruitingAccepts Healthy Volunteers

Cognition and Ultrasound

University of Minnesota

Start Date

6/1/2024

Completion Date

7/1/2028

Summary

Our primary goal is to investigate the role of Low-Intensity Focused Ultrasound (LIFU) neuromodulation on deep brain targets, and its potential to improve cognition

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * 18 years of age or older * Speak English (as assessed by their ability to read/answer survey questions) * May be required to score in the appropriate range on self-report measures Exclusion Criteria: * They have a neurological disorder which may impact their fMRI scan or cause their reaction to LIFU to differ from that of healthy adults. * They take any psychoactive medication. * They are unable to undergo fMRI scanning due to a contraindication such as claustrophobia, unremovable piercings, pregnancy, the presence of medical devices such as pacemakers, or a movement or sleep disorder. * Are pregnant, or may have reason to believe that they are pregnant. * They have a diagnosis of a psychiatric condition other than depression or anxiety

Interventions

DEVICE

Low-Intensity Focused Ultrasound (FUS or LIFU)

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Conditions

Healthy Participants

Locations

University of Minnesota

Minneapolis, Minnesota 55455

United States