NCT07239219NARecruitingAccepts Healthy Volunteers
The Impact of Irrisept in Reducing Urinary Tract Infection During Urethral Catheter Removal.
Ohio State University
Start Date
1/1/2026
Completion Date
1/1/2028
Summary
Given the high burden of post-catheter removal UTIs, this study aims to evaluate Irrisept instillation as a non-antibiotic intervention to reduce infection rates. By comparing Irrisept to saline irrigation, the study will provide critical insights into the efficacy of antiseptic bladder irrigation in preventing UTIs while minimizing antibiotic use. If successful, this approach could lead to new clinical guidelines for catheter removal protocols, improving patient outcomes and reducing healthcare costs.
Eligibility Criteria
Age Range: 18 years to No maximum
Inclusion Criteria:
1. Presenting to the urology clinic for catheter removal
2. Must be 18 years or older.
3. The patient must be able to understand and willing to provide informed consent as described in this study protocol.
4. Must be willing to complete a post-catheter removal survey
Exclusion Criteria:
1. Allergy or adverse reaction to chlorohexidine gluconate
2. Under the age of 18
3. Refuse to provide informed consent
4. On antibiotic therapy for any indication.
5. Women who are pregnant or breastfeeding
6. Signs of skin or systemic infection
7. Patients undergoing catheter exchange
Interventions
OTHER
0.05% Chlorhexidine Gluconate
OTHER
Normal Saline
Conditions
Urinary Tract InfectionAntibioticCatheter Infection
Locations
The Ohio State University
Columbus, Ohio 43212-3153
United States