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NCT07256717NARecruitingAccepts Healthy Volunteers

BPIT 5-Week Multi-Site Study: Movement Efficiency, Mobility & Neuromuscular Adaptation

MMSx Authority Institute for Movement Mechanics & Biomechanics Research Inc.

Start Date

10/10/2025

Completion Date

2/25/2026

Summary

This prospective, multi-site, single-arm interventional study evaluates the 5-Line Principle of Balanced Progressive Intensity Training (BPIT) over 5 weeks in healthy adults aged 18-65 years. All participants receive supervised BPIT sessions (3-5 per week) progressing through five intensity lines defined by anatomical landmarks and ground reaction force: Ground-Based (Low) Knee-Level (Low-Moderate) Standing (Moderate) Head-Level (Moderate-High) Plyometric (High-Impact) The study aims to quantify improvements in functional movement efficiency, joint mobility, postural control, strength adaptation, and heart-rate variability while monitoring safety and individual overload indicators.

Detailed Description

Primary Outcome Measures Change in Functional Movement Screen (FMS) total score from baseline to Week 5 Change in Y-Balance Test reach distance (composite score) Timeframe: Baseline and Week 5 Secondary Outcome Measures Change in 1-RM or estimated strength (squat, deadlift, overhead press) Change in resting HRV (RMSSD) Change in joint range of motion (goniometry) and postural sway Incidence of training-related discomfort or minor injury Timeframe: Baseline, weekly, and Week 5 Arms/Intervention Experimental: BPIT 5-Line Training Group Intervention: Behavioral: Balanced Progressive Intensity Training (BPIT) 5-Line Method Description: 5-week supervised progressive training using the BPIT 5-Line framework (ground-based → plyometric) Eligibility Ages Eligible: 18 Years to 65 Years Sexes Eligible: All Accepts Healthy Volunteers: Yes Inclusion Criteria Healthy adults with regular exercise history Able to attend 3-5 training sessions/week Signed informed consent Exclusion Criteria Recent injury (\<3 months) Known cardiovascular, metabolic, or orthopaedic contraindications Pregnancy Study Locations 13 Locations in India 2 Locations in USA, (Details of the location is uploaded on mmsxauthority.com webiste) MMSx Authority , USA, GFFI Fitness Academy, New Delhi BodyGNTX USA BFS/AIHFT-approved facilities Countries of Recruitment India U.S. FDA-regulated? No / No / No Human Subjects Protection Review Board Status Approved (or Submit for review if not yet) Board Name: Institutional Ethics Committee - MMSx Authority / GFFI Approval Number: BPIT-MULTI-2025-001 (or pending) Data Monitoring Committee No

Eligibility Criteria

Age Range: 18 years to 65 years

Inclusion Criteria: * Adults aged 18-65 years Generally healthy with regular physical activity history (at least 1-2 sessions per week for the past 3 months) Able to commit to 3-5 supervised training sessions per week for 5 weeks Willing and able to provide written informed consent Cleared by pre-screening (no acute injury, no contraindications) Exclusion Criteria: * Acute musculoskeletal injury within the past 3 months Known cardiovascular, metabolic, or orthopaedic conditions that contraindicate exercise Pregnancy or planning pregnancy Use of medications or supplements that significantly affect muscle recovery or performance (e.g., corticosteroids, anabolic agents) Inability to follow the BPIT protocol or attend required sessions

Interventions

BEHAVIORAL

Balanced Progressive Intensity Training (BPIT) 5-Line Method

Interested in This Trial?

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Conditions

Physical Fitness

Locations

BodyGNTX Fitness Institute

Columbus, Ohio 43220

United States

MMSx Authority Biomechanics Department

Powell, Ohio 43065

United States

MMSx AUTHORITY INSTITUTE FOR MOVEMENT MECHANICS & BIOMECHANICS RESEARCH (COORDINATING CENTER)

Powell, Ohio 43065

United States

Indian Institute of Kinesiology & Biomechanics Science (IIKBS)

Burhānpur, Madhya Pradesh 450331

India

Shri Mahaveer Ortho Clinic

Delhi, National Capital Territory of Delhi 110032

India

GFFI Fitness Academy

New Delhi, National Capital Territory of Delhi 110026

India

Active India Health & Fitness Trust (AIHFT)

New Delhi, National Capital Territory of Delhi 110063

India

Body Mechanics Gym P Ltd

New Delhi, National Capital Territory of Delhi 110092

India

Regain Fitness Zone

Greater Noida, Uttar Pardesh 201310

India

GFFI Fitness Academy

Agra, Uttar Pradesh 282005

India