NCT07282691RecruitingAccepts Healthy Volunteers
Validation of Clinical Outcome Measures Specific to mTBI-Related Oculomotor Disorders
Salus University
Start Date
4/1/2025
Completion Date
9/29/2028
Summary
The specific aim of this project is to validate clinical tests to be used as outcome measures in studies of mTBI-related vision problems.
Detailed Description
Participants with (n=50) and without (n=100) a history of mTBI will be recruited. Investigators will study the use of a series of visual endurance tests (tests that require sustained visual responses over a period of time). In addition to developing expected values for these tests, investigators will also after qualitative data about discomfort levels during testing.
Eligibility Criteria
Age Range: 18 years to 35 years
Inclusion Criteria:
* Diagnosis of mTBI within previous 1 to 6 months
* Distance visual acuity better than or equal to 20/25 in each eye
* Score \>21 on Convergence Insufficiency Symptom Survey
Exclusion Criteria:
* Diagnosis of moderate or severe TBI; \> 30-min loss of consciousness
* Not wearing required refractive error)
* Disease(s) known to affect oculomotor system (multiple sclerosis, Graves orbitopathy, myasthenia gravis, diabetes mellitus, or Parkinson disease)-Manifest strabismus or intraocular injury (evaluated at vision examination)
* Cognitive delays that may impact testing
Conditions
MTBI - Mild Traumatic Brain Injury
Locations
The Eye Institute
Philadelphia, Pennsylvania 19141
United States