Back to Trials
NCT07291245NARecruiting

Kawasaki MATCH Trial

University of California, San Diego

Start Date

3/1/2025

Completion Date

10/31/2026

Summary

Evaluating the impact of a machine-learning clinical decision support tool on provider practice when evaluating febrile patients with Kawasaki Disease (KD) and non-KD illnesses.

Detailed Description

Following laboratory evaluation, providers will be randomized to treat patients according to usual practice/standard of care vs. receiving clinical decision support from the Kawasaki MATCH tool - a previously validated machine-learning clinical decision support tool to identify Kawasaki Disease. The study aim is to evaluate the accuracy of Kawasaki MATCH prospectively when used at the point of care, as well as how this tool impacts clinical decisions including additional evaluation and hospital admission.

Eligibility Criteria

Age Range: No minimum to 17 years

Inclusion Criteria: * Measured or subjective fever for \>= 3 calendar days * One measured fever \>= 38.0 C (home or in ED) * One or more clinical feature of Kawasaki Disease including: * Rash * Conjunctival injection * Oropharyngeal changes * Extremity changes (erythema, edema, desquamation) * Cervical adenopathy (\>=1.5cm) * Infants \< 6 months of age with \>= 7 days of fever eligible even if none of the above clinical features * Requires IV/phlebotomy for clinical evaluation Exclusion Criteria: * Congenital or Acquired Immune function * Genetic disorders * Current systemic steroid, immunosuppression, or chemotherapy treatment (not including inhaled steroids)

Interventions

OTHER

Kawasaki MATCH

Interested in This Trial?

Contact the trial locations directly using the information below to learn more about enrollment.

Expressing interest lets you review the study and consent before we connect you with the research site.

Conditions

Kawasaki Disease

Locations

Rady Children's Hospital, San Diego

San Diego, California 92071

United States