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NCT07322367NARecruiting

A Mobile Patient Health Technology Intervention for Improving Lung Cancer Screening Rates in Eligible High Risk Patients

Wake Forest University Health Sciences

Start Date

3/25/2026

Completion Date

1/1/2027

Summary

To evaluate the real-world effectiveness and implementation strategies for mPATH-Lung, investigators propose a pragmatic, randomized controlled trial across an academic Learning Health System. The trial will contrast several approaches to participant outreach and will specifically target engaging fully powered cohorts of racial/ethnic minorities and rural residents.

Detailed Description

Primary Objective: Evaluate the real-world effectiveness of mPATH-Lung in increasing lung cancer screening rates across diverse populations. Secondary Objectives * Compare the differential effectiveness of three outreach strategies for engaging participants with mPATH-Lung across vulnerable rural or ethnic/racial minority population subgroups. * Estimate the additional revenue generated by mPATH-Lung through increased screening and downstream care. * Evaluate the potential for over-screening and the impact of applying HEDIS-based exclusion criteria

Eligibility Criteria

Age Range: 50 years to 77 years

Inclusion Criteria: Eligible patients will: * Meet the Medicare criteria for lung cancer screening, as updated in February 2022: * Age 50 - 77 years * Smoked at least 20 pack years * Current smoker or quit smoking within the past 15 years * Be established with a primary care provider within the Atrium Health Wake Forest Baptist health network (defined as having completed at least 1 primary care appointment in the past 6 months or have completed at least 2 primary care appointments within the past 18 months or being scheduled to see a health network primary care provider within the next 30 days). * Have a patient portal account or cellphone number listed in the electronic health record * Have a North Carolina address listed in the electronic health record Exclusion Criteria: The following patients will be excluded: * Patients flagged as needing a language interpreter in the electronic health record for any language other than Spanish (electronic messages and intervention are deliverable in English or Spanish only) * Those for whom lung cancer screening would be or may be inappropriate: electronic health record Prior history of lung cancer electronic health record Chest CT within the last 12 months electronic health record Those meeting the HEDIS COL-E measure exclusion criteria based on significant comorbidities and/or frailty.

Interventions

OTHER

Portal Message with Reminder Text Messages

OTHER

Text Message with Reminder Text Messages

OTHER

Portal message only

OTHER

Usual Care

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Conditions

Lung Cancer

Locations

Atrium Health Wake Forest Baptist

Winston-Salem, North Carolina 27157

United States