NCT07378813NARecruiting
Low Versus High Load Training and Parkinson's Disease
University of Miami
Start Date
1/30/2026
Completion Date
5/30/2027
Summary
This study will compare the effects of high-load resistance training to low-load resistance training, on measures of muscle strength and power and tests of daily performance in older adults with Parkinson's disease.
Eligibility Criteria
Age Range: 50 years to 85 years
Inclusion Criteria:
* Parkinson's Disease Hoehn \& Yahr Stages 1-3
* Able to walk 50m unassisted
* Able to understand and communicate in English
* A Montreal Cognitive Assessment (MoCA) score above 18
Exclusion Criteria:
* Uncontrolled cardiovascular or other neuromuscular disease that prevent participation in a training program
* Any systemic inflammatory or autoimmune conditions such as rheumatoid arthritis, or other serious concomitant medical illness
* Unresolved injury or surgery to the upper or lower limbs that prevents weight training.
Interventions
BEHAVIORAL
Low-Load Resistance Training
BEHAVIORAL
High-Load Resistance Training
Conditions
Activity, Motor
Locations
Laboratory of Neruomuscular Research and Active Aging
Coral Gables, Florida 33147
United States