NCT07378839NARecruiting
Alternate Nostril Breathing (ANB) for 1st Trimester Nausea and Vomiting
University of Minnesota
Start Date
2/10/2026
Completion Date
3/31/2027
Summary
This is a prospective, two-arm, non-blinded randomized controlled study designed to evaluate the effects of a one-week alternate nostril breathing (ANB) intervention on nausea and vomiting severity in pregnant individuals during their first trimester.
Eligibility Criteria
Age Range: 18 years to No maximum
Inclusion Criteria:
* Pregnant individuals aged 18 years or older
* Viable pregnancy with a gestational age between 6 0/7 - 12 6/7 weeks of gestation, confirmed by last menstrual period or ultrasound
* Diagnosed with mild to moderate NVP (PUQE-24 score between 4-12)
* Ability to understand and read English
Exclusion Criteria:
* Severe nausea and vomiting, defined as a PUQE score \>12, or diagnosis of hyperemesis gravidarum requiring hospitalization or intravenous fluid therapy
* Pre-existing, active or acute respiratory conditions (e.g., asthma, COPD)
* History of severe anxiety disorders affecting breathing patterns
* Known deviated nasal septum
* Nausea and vomiting that pre-dates the pregnancy or is suspected to be due to a etiology other than pregnancy
Interventions
BEHAVIORAL
Alternate Nostril Breathing
Conditions
Pregnancy EmesisNausea
Locations
University of Minnesota
Minneapolis, Minnesota 55455
United States