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NCT07378839NARecruiting

Alternate Nostril Breathing (ANB) for 1st Trimester Nausea and Vomiting

University of Minnesota

Start Date

2/10/2026

Completion Date

3/31/2027

Summary

This is a prospective, two-arm, non-blinded randomized controlled study designed to evaluate the effects of a one-week alternate nostril breathing (ANB) intervention on nausea and vomiting severity in pregnant individuals during their first trimester.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Pregnant individuals aged 18 years or older * Viable pregnancy with a gestational age between 6 0/7 - 12 6/7 weeks of gestation, confirmed by last menstrual period or ultrasound * Diagnosed with mild to moderate NVP (PUQE-24 score between 4-12) * Ability to understand and read English Exclusion Criteria: * Severe nausea and vomiting, defined as a PUQE score \>12, or diagnosis of hyperemesis gravidarum requiring hospitalization or intravenous fluid therapy * Pre-existing, active or acute respiratory conditions (e.g., asthma, COPD) * History of severe anxiety disorders affecting breathing patterns * Known deviated nasal septum * Nausea and vomiting that pre-dates the pregnancy or is suspected to be due to a etiology other than pregnancy

Interventions

BEHAVIORAL

Alternate Nostril Breathing

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Conditions

Pregnancy EmesisNausea

Locations

University of Minnesota

Minneapolis, Minnesota 55455

United States