NCT07398209NARecruiting
GCC 2546- Motion Management
University of Maryland, Baltimore
Start Date
4/14/2026
Completion Date
4/1/2029
Summary
The purpose of this study is to assess a real time motion tracking of lung tumors and important organs next to the tumor while breathing during a participant's radiation treatment. This will be assessed through a four-dimensional magnetic resonance imaging (MRI) scan before starting your radiation treatment and x-ray fluoroscopy images that are taken during radiation
Eligibility Criteria
Age Range: 18 years to No maximum
Inclusion Criteria:
1. Adult (≥18 years) patients (both sexes) with histologically diagnosed Stage II-IIIb NSCLC
2. Patients to be treated with definitive external beam photon radiotherapy with or without systemic therapy (e.g., chemotherapy, immunotherapy).
3. No restrictions on number radiotherapy fractions, or location/number of lesions
4. ECOG performance status ≤ 3
5. Ability to undergo MRI scans
6. Patient has signed informed consent document and agreed to study procedures
Exclusion Criteria:
1. Pre-existing contraindications for MRI, such as any MRI-conditional or MRI-unsafe foreign objects within the body, non-removable ear cochlear or eye implant, aneurysm clip, cardiac pacemaker/wires, internal defibrillator, tissue expander, recent stent placement, penile prosthesis, medication patch, artificial limb, pregnancy, and claustrophobia
2. Women who are pregnant or trying to get pregnant (self-reported)
3. Pain in supine position or inability to raise arm above head in supine position
Interventions
OTHER
MRI
Conditions
Lung Cancer (NSCLC)Radiation
Locations
University of Maryland Greenebaum Cancer Center
Baltimore, Maryland 21201
United States