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NCT07402577Recruiting

Brief Title Mechanisms of Cancer-Related Pain and Opioid Use Among Adolescents and Young Adult Sarcoma Survivors: Pilot Feasibility Study

Roswell Park Cancer Institute

Start Date

3/30/2026

Completion Date

2/1/2028

Summary

This study generates information on the feasibility and acceptability of a 3-month ecological momentary assessment (EMA) protocol to assess chronic pain and opioid use in adolescent and young adult (AYA) sarcoma survivors.

Detailed Description

PRIMARY OBJECTIVES: I. Evaluate the feasibility and acceptability of a 3-month EMA protocol in AYA sarcoma survivors. II. Quantify variability in pain and opioid use over a 3-month period for AYA sarcoma survivors. III. Identify associations between biopsychosocial mechanisms (e.g., pain beliefs, worry) and pain and opioid use outcomes. OUTLINE: This is an observational study. Patients complete baseline questionnaires, daily EMA surveys and an interview on study.

Eligibility Criteria

Age Range: 12 years to 70 years

Inclusion Criteria: * All genders between the ages of 12-24 (inclusive) at sarcoma diagnosis. * Any age \< 70 at the time of study enrollment. * No evidence of disease and/or enrolled in survivorship care. * Clinically meaningful pain related to disease or its treatments at baseline (defined as 3 or greater on a 0-10 Numerical Rating Scale). * Willing to attend the baseline appointment in person. * Access to internet-capable smartphone. * Access to internet on an occasional basis. * Willing and able to complete Ecological Momentary Assessments (EMAs) on internet-capable smartphone for a 3-month period after enrollment. * Ability to understand and provide informed consent/assent. Exclusion Criteria: * \* Currently receiving active cancer-directed therapy. * Unable to read or fluently speak English. * Determined by clinical staff to have preexisting or cancer-associated cognitive impairment that could interfere with study participation. * Acutely suicidal (e.g. intent or plan) or, with unstable medical or psychiatric condition verified by licensed study staff. * Characteristics related to inability to complete the study protocol.

Interventions

OTHER

Non Intervention Study

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Conditions

SarcomaChildhood Sarcoma of Soft Tissue

Locations

Roswell Park Comprehensive Cancer Center

Buffalo, New York 14263

United States