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NCT07425119NARecruiting

Project Q: Cue-based Treatment Intervention to Promote Cessation Among People Who Smoke Lightly or Non-daily

Duke University

Start Date

7/7/2026

Completion Date

6/1/2028

Summary

This study aims to test the feasibility and acceptability of a remotely delivered cue-based treatment intervention to promote smoking cessation among people who smoke lightly or non-daily. Secondary objectives include assessing preliminary efficacy on cessation and examining cue reactivity. Participants will be randomized to CBT only or CBT + cue-based treatment, with assessments at baseline, end-of-treatment, 6 months, and 12 months.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Age ≥18 * Able to read and understand English or Spanish * Smoke 1-10 cigarettes/day on at least 4 days of the past two weeks for the last year * Willing to try quitting in next 30 days * Access to cell phone with texting capabilities Exclusion Criteria: * Current participation in another smoking cessation study * Unable to provide consent * Refusal to abstain from e-cigarettes or other tobacco products * Use of medications affecting smoking cessation (e.g., Chantix, Wellbutrin)

Interventions

BEHAVIORAL

Cognitive Behavioral Therapy (CBT)

BEHAVIORAL

Cue-based treatment intervention

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Conditions

Tobacco Use Disorder

Locations

Duke University

Durham, North Carolina 27701

United States