A Study to Learn About mRNA Vaccines Against Influenza in Adults
Start Date
2/23/2026
Completion Date
6/22/2027
Summary
The purpose of this study is to learn about safety in participants taking the study vaccine (mRNA-based vaccine) and the ability of the study vaccine to trigger the body's immune response, targeting the flu virus (influenza virus). This study is seeking healthy participants 18 years of age or older. All participants in this study will receive only 1 dose in their arm, to deliver one of the experimental flu vaccines or one of the approved flu vaccines used for comparison. Participants will take part in this study for about 6 months, and participants will need to visit the study site at least 3 times. A blood sample will be taken at each of the 3 planned study visits and a swab from inside the nose will be taken at the first study visit.
Eligibility Criteria
Age Range: 18 years to No maximum
Interventions
Vaccine Candidate #1
Vaccine Candidate #2
Vaccine Candidate #3
Vaccine Candidate #4
Vaccine Candidate #5
Vaccine Candidate #6
TIV1 or TIV2
Conditions
Locations
AMR Clinical
Mobile, Alabama 36608
United States
Diablo Clinical Research, LLC d/b/a Flourish Research
Walnut Creek, California 94598
United States
Clinical Research Consulting, LLC
Milford, Connecticut 06460
United States
George Washington Medical Faculty Associates
Washington D.C., District of Columbia 20037
United States
Indago Research & Health Center, Inc
Hialeah, Florida 33012
United States
Palm Springs Community Health Center
Miami Lakes, Florida 33014
United States
Clinical Research Atlanta
Stockbridge, Georgia 30281
United States
East-West Medical Research Institute
Honolulu, Hawaii 96814
United States
AMR Clinical
Kansas City, Missouri 64114
United States
Rochester Clinical Research, LLC
Rochester, New York 14609
United States
DM Clinical Research - Philadelphia
Philadelphia, Pennsylvania 19107
United States
SMS Clinical Research LLC
Mesquite, Texas 75149
United States
DM Clinical Research
Tomball, Texas 77375
United States
J. Lewis Research, Inc. / Foothill Family Clinic
Salt Lake City, Utah 84109
United States
Charlottesville Medical Research Center, LLC
Charlottesville, Virginia 22911
United States