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NCT07434635PHASE4Recruiting

APPRAISE: Assessment of Pain and Posterior Synechiae Reduction With Atropine, an Investigation of Post-Surgical Eyes

University of California, San Francisco

Start Date

3/10/2026

Completion Date

2/1/2029

Summary

The study will evaluate whether atropine eyedrops are beneficial when used after certain eye surgeries.

Detailed Description

Atropine eyedrops are often used after certain eye surgeries. This study will compare several outcomes following surgery in patients either using or not using this treatment.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * patient undergoing vitrectomy surgery * able to give informed consent Exclusion Criteria: * post-operative eyedrop regimens that include topical non steroidal anti-inflammatory medications * subjects with altered post-operative eyedrop schedule for enhanced inflammation control * documented allergy to atropine

Interventions

DRUG

Atropine 1%

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Conditions

Eye Disorders

Locations

University of California, San Francisco

San Francisco, California 94143

United States