NCT07440017NARecruitingAccepts Healthy Volunteers
Older Age and Generalization
Caitlin Bowman
Start Date
6/15/2026
Completion Date
12/31/2029
Summary
The goal of this clinical is to learn how the brain supports different kinds of memory decisions in healthy young and older adults. The main question it seeks to answer is: Do older adults make memory decisions by integrating across experiences? Young (aged 18-30 years) and older (aged 65-80 years) participants will complete a memory task while undergoing functional MRI to measure their brain responses. Researchers will compare brain measures of integration in older adults to those of young adults to see if integration increases in older age.
Eligibility Criteria
Age Range: 18 years to 80 years
Inclusion Criteria:
* Either aged 18-30 years (young adults) or aged 65-80 years (older adults) (self-report)
* Fluent in English (self-report)
* Right-handed (self-report)
* Cognitively healthy (self report verified by score \> 24 on Montreal Cognitive Assessment)
* Self-reported normal or corrected-to-normal vision
Exclusion Criteria:
* Self-reported neurological disorder (e.g., Alzheimer's or Parkinson's disease)
* Self-reported uncontrolled hypertension, diabetes, or thyroid disorder
* Having conditions or devices that are unsafe for MRI (assessed via imaging center's MRI safety screening form)
* Self-reported difficulty lying still on one's back for 1-2 hours
Interventions
BEHAVIORAL
Memory decision type
Conditions
Aging
Locations
University of Wisconsin-Milwaukee
Milwaukee, Wisconsin 53211
United States