NCT07442851NARecruiting

SickleFit Exercise and Nutrition Study

Duke University

Start Date

4/8/2026

Completion Date

1/1/2028

Summary

To goal of this study is to pilot the SickleFit exercise and nutrition intervention in adults with sickle cell disease in a randomized control trial

Detailed Description

Investigators will pilot the SickleFit personalized exercise plus dietitian-facilitated nutrition intervention randomized control trial in adults (age ≥ 35 years) with sickle cell disease.

Eligibility Criteria

Age Range: 35 years to No maximum

Inclusion Criteria: * Laboratory-confirmed diagnosis of sickle cell disease (any genotype) * Understand and speak English by self-report * Age ≥ 35 years old Exclusion Criteria: * Oxygen dependence * Unstable cardiac disease * Wheelchair-bound * Diagnosed with severe cognitive impairment based on ICD-10 codes or reported by their outpatient provider * Unable to self-consent * Severe uncorrected visual or auditory impairment * Pregnant * Successfully treated with hematopoietic stem cell transplantation or gene therapy for sickle cell disease

Interventions

BEHAVIORAL

SickleFit Exercise plus Nutrition

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Conditions

Sickle Cell DiseaseAging

Locations

Duke University

Durham, North Carolina 27710

United States